#### Fang X. Wu B.Sc., M.Sc., Ph.D., P.Eng.

Professor, Department of Mechanical Engineering and Division of Biomedical Engineering

Graduate Chair, Division of Biomedical Engineering

- Room 3B42 Engineering Building
- (306) 966-5280
- fangxiang.wu@usask.ca
- http://homepage.usask.ca/~faw341

Biography

#### Education and Experience

B.Sc.,M.Sc. (DLUT), Ph.D. (NWPU), Ph.D. (Saskatchewan), P. Eng.

**Specialization**

- Bionetwork analysis,
- Network control theory and its applications,
- Drug target identification,
- Biomedical signal and image processing and analysis,
- System identification and parameter estimation,
- Large scale biological data analysis,
- Machine learning

#### Current and Past Projects

- Development of Methodologies for modeling and designing biological systems
- Development of real-time control methodologies for tandem mass spectrometry
- Computational bioengineering Laboratory
- Control engineering approaches to gene regulatory networks

**Positions for graduate students in Systems Biology are now available in my research group.** I am interested in recruiting high-caliber graduate students who have expertise in the areas of my research. Top-tier control and systems, computer science amd applied mathematics students who are self-motivated and have publications in relevant scientific journals are encourages to apply.

Publications

##### Refereed Journal Publications

- Yuan, Z., Shi, J.H., Lin, W.J., Chen, B.L. and Wu, F.X. (2012). Features-based deisotoping method for tandem mass spectra,
*Advances in Bioinformatics*,**2011**(ID 210805), 1-2. - Tian, L.P. and Wu, F.X. (2012). Stability and Bifurcations Analysis of Models for Zebrafish Somitogenesis,
*IEEE Transactions on Nanobioscience*,**10**(4), 239-247. - Wu, F.X. (2012). Stability and Bifurcation of Ring-Structured Genetic Regulatory Networks with Time Delays,
*IEEE Transactions on Circuits and Systems I*,**59**(6), 1312-1320. - Han, L.L., Wu, F.X., Sheng, J. and Ding, F. (2012). Two recursive least squares parameter estimation algorithms for multirate multiple-input systems by using the auxiliary model,
*Mathematics and Computers in Simulation*,**82**(5), 777-789. - Liu, L.Z., Wu, F.X. and Zhang, W. (2012). Inference of Biological S-system Using Separable Estimation Method and Genetic Algorithm,
*IEEE/ACM Transactions on Computational Biology and Bioinformatics*,**9**(4), 955-965. - Liang, X.J., Xia, Z.H., Zhang, L.W. and Wu, F.X. (2012). Inference of Gene Regulatory Subnetworks from Time Course Gene Expression Data,
*BMC Bioinformatics,*,**13**(S9: S3), 1-10. - Tian, L.P., Liu, L.Z., Zhang, Q.W. and Wu, F.X. (2011). Nonlinear Model-based methods for clustering periodically expressed genes,
*TheScientificWorldJOURNAL*,**11**, 2051-2061. - Wu, F.X. (2011). Global and Robust Stability Analysis of Genetic Regulatory Networks with Time-Varying Delays and Parameter Uncertainties,
*IEEE Transactions on Biomedical Circuits and Systems*,**5**(4), 391-398. - Wu, F.X. (2011). Delay-Independent Stability of Genetic Regulatory Networks,
*IEEE Transaction on Neural Networks*,**22**(11), 1685-1693. - Shi, J.H. and Wu, F.X. (2011). Peptide Charge State Determination of Tandem Mass Spectra from Low-Resolution Collision Induced Dissociation,
*BMC Proteome Science*,**9**(S1:S3), 1-8. - Yan, Y., Zhang, S.G. and Wu, F.X. (2011). Applications of Graph Theory in Protein Structure Identification,
*BMC Proteome Science,*,**9**(S1:S17), 1-10. - Zhang, J., McQuillan, I. and Wu, F.X. (2011). Speed Improvements of Peptide-Spectrum Matching Using SIMD Instructions,
*Proteomics*,**11**(19), 3779-3785. - Cheng, L., Hou, Z.G., Lin, Y., Tan, M., Zhang, W. and Wu, F.X. (2011). A Recurrent Neural Network for Non-Smooth Convex Optimization Problems with an Application to the Identification of Genetic Regulatory Networks,,
*IEEE Transaction on Neural Networks*,**22**(5), 714-726. - Wu, F.X. and Huan, J. (2011). Special Focus on Bioinformatics and Systems Biology,
*IEEE/ACM Transactions on Computational Biology and Bioinformatics*,**8**(2), 292-293. - Ding, J.D., Shi, J.H. and Wu, F.X. (2011). SVM-RFE based feature selection for tandem mass spectrum quality assessment,,
*International Journal of Data Mining and Bioinformatics*,**5**(1), 73-88. - Zou, A.M., Shi, J.H., Ding, J.D. and Wu, F.X. (2010). Charge state determination of peptide tandem mass spectra using support vector machine (SVM),
*IEEE Transaction on Information Technology in Biomedicine*,**14**(3), 552-558. - Wu, F.X., Shi, Z.K. and Mu, L. (2010). Estimating parameters in the caspase activated apoptosis system,
*International Journal of Biomedical Engineering and Technology*,**4**(4), 338-354. - Wu, F.X., Mu, L. and Shi, Z.K. (2010). Estimation of Parameters in Rational Reaction Rates of Molecular Biological Systems via Weighted Least Squares,
*International Journal of Systems Science*,**40**(1), 73-80. - Wu, F.X. and Zhang, W. (2010). Dynamic model-based method for selecting genes from time-course expression profiles,
*IEEE Transaction on Information Technology in Biomedicine*,**14**(1), 16-22. - Koh, C., Wu, F.X., Selvaraj, G. and Kusalik, A. (2009). "Using a state-space model and location analysis to infer time-delayed gene regulatory networks",,
*EURASIP Journal on Bioinformatics and Systems Biology*,**2009**(Article ID 484601), 1-14. - Shi, J.H. and Wu, F.X. (2009). Protein Inference by Assembling Peptides Identified from Tandem Mass Spectra,
*Current Bioinformatics*,**4**(3), 226-233. - Ding, J.D., Shi, J.H. and Wu, F.X. (2009). Quality assessment of tandem mass spectra by using a weighted k-means,
*Clinical Proteomics*,**5**(1), 15-22. - Hang, X.Y. and Wu, F.X. (2009). l1 least square for cancer diagnosis using gene expression data,
*Journal of Computer Science and System Biology*,**2**(2), 167-173.. - Hang, X.Y. and Wu, F.X. (2009). Sparse Representation for the Classification of Tumors Using Gene Expression Data,
*Journal of Biomedicine and Biotechnology*,**2009**(Article ID 403689), 1-6. - Ding, J.D., Shi, J.H., Poirier, G.G. and Wu, F.X. (2009). A novel approach to denoising ion trap tandem mass spectra,
*BMC Proteome Science*,**7**(:9), 1-12. - Hu, X., Ng, M., Wu, F.X. and Sokhansanj, B.A. (2009). Mining, modeling and evaluation of sub-networks from large biomolecular networks and its comparison study,
*IEEE Transaction on Information Technology in Biomedicine*,**13**(2), 184-194. - Wu, F.X., Xia, Z.H. and Mu, L. (2009). Finding significantly expresses genes from time-course expression profiles,
*International Journal of Bioinformatics Research and Applications*,**5**(1), 50-63. - Wu, F.X. (2009). Delay-Independent Stability of Genetic Regulatory Networks with Time Delays,
*Advances in Complex Systems*,**12**(1), 3-19. - Zou, A.M., Wu, F.X., Ding, J.D. and Poirier, G.G. (2009). Quality assessment of tandem mass spectra using support vector machine (SVM),
*BMC Bioinformatics*,**10**(S1:S49), 1-11. - Wu, F.X., Ding, J.R. and Poirier, G.G. (2008). An approach to Assessing Peptide Mass Spectral Quality without Prior Information,
*International Journal of Functional Informatics and Personalised Medicine*,**1**(2), 140-155. - Wu, F.X. (2008). A genetic weighted k-means algorithm for clustering gene expression data,
*BMC Bioinformatics*,**9**(S6), S12-0. Available online at: http://www.biomedcentral.com/1471-2105/9/S6/S12 - Wu, F.X., Gagne, P., Droit, A. and Poirier, G.G. (2008). Quality assessment of peptide tandem mass spectra,
*BMC Bioinformatics*,**9**(S6), S13-0. Available online at: http://www.biomedcentral.com/1471-2105/9/S6/S13 - Wu, F.X. (2008). Gene Regulatory Network Modelling: A state-space approach,
*International Journal of Data Mining and Bioinformatics*,**2**(January), 1-14. - Hu, X. and Wu, F.X. (2007). Mining and state-space modeling and verification of sub-networks from large biomolecular networks,
*BMC Bioinformatics*,**8**, 324-0. Available online at: http://www.biomedcentral.com/1471-2105/8/324/abstract - Wu, F.X. (2007). Inference of Gene Regulatory Networks and Its Validation,
*Current Bioinformatics*,**2**(March), 139-144. - Wu, F.X., Zhang, C. and Kusalik, A. (2006). "Determination of the Minimum Number of Microarray Experiments for Discovery of Gene Expression Patterns".,
*BMC Bioinformatics*,**7**(December 2006), 13-0. - Wu, F.X., Zhang, C. and Kusalik, A.J. (2006). Determination of the Minimum Number of Microarray Experiments for Discovery of Gene Expression Patterns,
*BMC Bioinformatics*,**7**(Suppl. 4 - S13), 1-1. - Zhang, C.H., Bickis, M.G., Wu, F.X. and Kusalik, A. (2006). Optimally-connected hidden Markov models for predicting MHC-binding peptides,
*Journal of Bioinformatics and Computational Biology*,**4**, 959-980. - Wu, F., Gagne, P., Droit, A. and Poirier, G.G. (2006). RT-PSM, a real-time program for peptide-spectrum matching with statistical significance,
*Rapid Communications in Mass Spectrometry*,**22**, 1199-1208. - Wu, F., Zhang, W.J. and Poirier, G.G. (2005). Inferring gene regulatory networks with time delays using genetic algorithm,
*Systems Biology*,**152**, 67-74. - Wu, F., Zhang, W.J. and Kusalik, A.J. (2005). Dynamic model-based clustering for time-course gene expression data,
*Journal of Bioinformatics and Computational Biology*,**3**, 821-836. - Wu, F., Zhang, W.J., Li, Q., Ouyang, P.R. and Zhou, Z.X. (2005). Control of hybrid machines with 2-DOF for trajectory tracking problems,
*IEEE Transactions on Control Systems Technology*,**13**, 338-342.

##### Refereed Conference Proceedings

- Tian, L.P., Liu, L.Z. and Wu, F.X. (2012). State Estimation for Genetic Regulatory Networks, iCBBE2012, Shanghai, China, May 17-20, (4 pages) (CD Rom).
- Chen, B.L., Yan, Y., Shi, J.H., Zhang, S.G. and Wu, F.X. (2011). Improved graph entropy-based method for detecting protein complexes, IEEE BIBM, Atlanta, USA, Nov 12-15, 123-126.
- Tian, L.P. and Wu, F.X. (2011). Delay-Dependent Stability for Genetic Regulatory Networks, IEEE BIBM 2011, Atlanta, USA, Nov 12-15, 197-201.
- Liang, X.J., Xia, Z.H., Zhang, L.W. and Wu, F.X. (2011). Modeling Gene Regulatory Subnetworks from Time Course Gene Expression Data, IEEE BIBM 2011, Atlanta, USA, Nov 12-15, 216-221.
- Shi, J.H., Chen, B.L. and Wu, F.X. (2011). Improving accuracy of peptide identification with consistency between peptides, EEE BIBM 2011, Atlanta, Nov 12-15, 191-196.
- Chen, B.L., Liu, L.Z. and Wu, F.X. (2011). Inferring stable gene regulatory networks from multiple time course gene expression datasets, IEEE ISB2011, Zhuai, China, Sept 2-4, 12-17.
- Tian, L.P., Liu, L.Z. and Wu, F.X. (2011). Estimating Parameters in Genetic Regulatory Networks with SUM Logic, IEEE EMBC11, Boston. USA, Aug. 30-Sept. 3, 1371-1374.
- Tian, L.P., Lu, H.Y. and Wu, F.X. (2011). Nonlinear Model-Based Clustering for Periodically Expressed Gene Profiles, The 7th International Symposium on Bioinformatics Research and Applications (ISBRA, 11), Changsha, Hunan, China, May 27-29, 2011, 62-66 (CD Rom).
- Tian, L.P., Liu, L.Z. and Wu, F.X. (2011). Identification of Pseudo-Periodic Gene Expression Profiles, The 2011 International Conference on Bioinformatics & Computational Biology, Las Vegas, Nevada, USA, July 18-21, 2011, 42-46.
- Zhang, J., McQuillan, I. and Wu, F.X. (2011). Parallelizing Peptide-Spectrum Scoring Using Modern Graphics Processing Units, IEEE ICCABS'11, Orlando. Florida, USA, Feb 2-5, 208-213.
- Tian, L.P., Liu, L.Z. and Wu, F.X. (2010). Parameter estimation method for Periodical Gene Identification, iCBBE2011, Wuhan, Jiangsu, China, May 10-12, (4 pages) (CD Rom).
- Liu, L.Z., Wu, F.X., Han, L.L. and Zhang, W. (2010). Structure Identification and Parameter Estimation of Biological S-systems, IEEE BIBM2010, Hong Kong, China, December 18-21, 329-334.
- Tian, L.P., Liu, L.Z. and Wu, F.X. (2010). Detecting Nearly periodical Expressed Genes from Their Microarray Time-Course Expression, IASTED 2010, Cambridge, Massachusetts, USA, November 1 ? 3,, Paper No. 8.
- Wu, F.X., Liu, L.Z. and Xia, Z.H. (2010). Identification of gene regulatory networks from time course gene expression data, IEEE EMBC2010, Buenos Aires, Argentina, August 31-September 4, 795-798.
- Tian, L.P., Liu, L.Z. and Wu, F.X. (2010). Parameter Estimation Method for Improper Fractional Models and Its Application to Molecular Biological Systems, IEEE EMBC2010, Buenos Aires, Argentina, August 31-September 4, 1477-1480.
- Li, S., Burton, R.T., Habibi, S., Schoenau, G.J. and Wu, F.X. (2010). Investigation of the Acceleration Effect on Dynamic Friction of EHA System, Bath/ASME Symposium on Fluid Power and Motion Control (FPMC 2010), Bath, UK, Sept 15-18, Paper No. N/A, (CD Rom).
- Shi, J.H., Lin, W.J. and Wu, F.X. (2010). Statistical Analysis of Mascot Peptide Identification with Active Logistic Regression, The 4th International Conference on Bioinformatics and Biomedical Engineering, Chengdu, Sichuan, China, June 18-20, (4 pages) (CD Rom).
- Tian, L.P., Mu, L. and Wu, F.X. (2010). Iterative Linear Least Squares Method of Parameter Estimation for Linear-Fractional Models of Molecular Biological Systems, The 4th International Conference on Bioinformatics and Biomedical Engineering, Chengdu, Sichuan, China, June 18-20, (4 pages) (CD Rom).
- Tian, L.P., Mu, L. and Wu, F.X. (2010). Alternating Constraint Least Squares Parameter Estimation for S-System Models of Biological Networks, The 4th International Conference on Bioinformatics and Biomedical Engineering, Chengdu, Sichuan, China, June 18-20, (4 pages) (CD Rom).
- Wu, F.X. and Mu, L. (2009). Parameter estimation in rational models of molecular biological systems, The 31th Annual International Conference of IEEE in Medicine and Biology Society, Minneapolis, Minnesota,USA, September 2-6, 3263-3266.
- Ding, J.D., Shi, J.H. and Wu, F.X. (2009). Model based clustering for tandem mass spectrum quality assessment, The 31th Annual International Conference of IEEE in Medicine and Biology Society, Minneapolis, Minnesota, USA, September 2-6, 6747-6750.
- Ding, J.D. and Wu, F.X. (2009). Feature selection for tandem mass spectrum quality assessment via sparse logistical regression, The 3rd International Conference on Bioinformatics and Biomedical Engineering, Beijing, China, June11-13, (4 pages) (CD Rom).
- Wu, F.X. and Mu, L. (2009). Separable Parameter Estimation Method for Nonlinear Biological System, The 3rd International Conference on Bioinformatics and Biomedical Engineering, Beijing, China, June11-13, (4 pages) (CD Rom).
- Hang, X.Y., Dai, W., Wu, F.X. and Milenkovic, O. (2009). Subspace pursuit for gene profile classification, IEEE International Workshop on Genomic Signal Processing and Statistics, Minneapolis, Minnesota, USA, May 17-19, (4 pages) (CD Rom).
- Ding, J.D., Zou, A.M., Shi, J.H. and Wu, F. (2008). Feature selection for tandem mass spectrum quality assessment, IEEE BIBM08, Philadelphia, PA, USA,, November 3-5, 310-313.
- Wu, F. (2008). Detecting significantly expressed genes from time-course expression profiles and its validation, IEEE BIBM08, Philadelphia, PA, USA,, November 3-5, 170-175.
- Wu, F.X. (2008). Stability and Oscillation of Genetic Regulatory Networks with Time Delays, IEEE BIBE08, Athens, October 8-10, Paper No. BIBE.2008.4696728, (6 pages).
- Zou, A.M., Ding, J.D., Shi, J.H. and Wu, F.X. (2008). Charge state determination of peptide tandem mass spectra using support vector machine (SVM),, IEEE BIBE08, Athens, October 8-10, Paper No. BIBE.2008.4696680, (6 pages).
- Hou, Z.G., Zou, A.M., Wu, F.X., Cheng, L. and Tan, M. (2008). Adaptive dynamic surface control of a class of uncertain nonlinear systems in pure-feedback form using fuzzy backstepping approach, Fourth Annual IEEE Conference on Automation Science and Engineering, Washington DC, August 23-36, 821-826.
- Wu, F.X., Mu, L. and Luo, R.Z. (2008). Complexity analysis and optimal experimental design for parameter estimation of biological systems, Proceedings of 2008 IEEE Canadian Conference on Eectrical and Computer Engineering ( IEEE CCECE'08 ), Niagara Falls, ON, Canada, May 4-7, 393-397.
- Wu, F.X., Ding, J.R. and Poirier, G.G. (2007). A framework for mass spectral quality assessment without prior information, IEEE Bioinformatics and Bioengineering (BIBE), Boston, MA, USA, Oct 14-17, 1419-1423.
- Wu, F.X. (2007). A genetic weighted k-means algorithm for clustering gene expression data, The symposium of Computations in Bioinformatics and Bioscience (SCBB), University of Iowa, August 13-15, 68-75.
- Wu, F.X. (2007). Estimation of parameters in the linear-fractional models, The 29th Annual International Conference of IEEE in Medicine and Biology Society (IEEE EMBC), Lyon, France, August 23-26, 1086-1089.
- Wu, F.X. (2007). Stability analysis of genetic regulatory networks with multiple time delays, The 29th Annual International Conference of IEEE in Medicine and Biology Society (IEEE EMBC), Lyon, France, August 23-26, 1387-1390.
- Hu, X., Wu, F.X., Ng, M. and Sokhansanj, B. (2007). Mining and dynamic simulation of sub-networks from large biomolecular networks (Received best parper award), The International Conference on Artificial Intelligence (ICAI), Las Vegas, Nevada, USA, June 25-28, 806-813.
- Wu, F.X. (2007). Significance analysis of time-course gene expression profiles, The International Symposium on Bioinformatics Research and Applications (ISBRA), Atlanta, GA, USA, May 7-10, Paper No. LNBI 4463, 13-24.
- Wu, F., Zhang, W.J. and Kusalik, A.J. (2006). On Determination of Minimum Sample Size for Discovery of Temporal Gene Expression Pattern, In Proceedings of the International MultiSymposiums on Computer and Computational Sciences, HangZhou, China, June 20-24.
- Wu, F., Gagne, P., Droit, A. and Poirier, G.G. (2006). Quality Assessment of Peptide Tandem Mass Spectra, Proceedings of the International Multi-Symposiums on Computer and Computational Science (IMSCCS), ,, Hang Zhou PRC, June 20-24, 2006, 243-250.
- Wu, F., Zhang, W.J. and Kusalik, A. (2006). On Determination of Minimum Sample Size for Discovery of Termporal Gene Expression Patterns, Proceedings of the International Multi-Symposiums on Computer and Computational Science (IMSCCS), Hang Zhou PRC, June 20-24, 2006, 96-103.

##### Conference Presentations / Poster Presentations

- Shi, J.H. and Wu, F.X. (2011). A feedback framework for protein inference from peptides identified from tandem mass spectra, Joint CNPN 2011 & ETP 2011 Symposium, Banff, Alberta, Canada, May 8-11.
- Wu, F.X. (2010). Identification of Periodically Expressed Genes from Their Time-Course Expression Profiles, International Symposium on Bioinformatics Research and Applications, Storrs, CT, USA, May 23-26, (12-15 pages).
- Zhang, J., McQuillan, I. and Wu, F.X. (2010). Parallel Algorithm for Speeding up Peptide-Spectrum Matching, Canadian National Proteomics Network 2nd Symposium - New Frontiers in Proteomic Research, Montreal, QC, Canada, May 9-10.
- Ding, J.D., Poirier, G.G. and Wu, F.X. (2009). A real-time control workflow for tandem mass spectrum acquisition, 4th International Symposium on Enabling Technologies for Proteomics, Vancouver, BC, Canada, May 14.
- Wu, F., Gagne, P., Droit, A. and Poirier, G.G. (2005). Quality Assessment of Peptide CID Spectra Acquired by Tandem Mass Spectrometry, The 2nd Annual Symposium on Enabling Technologies for Proteomics,, Calgary, AB, Canada, Sept 22-23, 2005., Paper No. 15.

##### Published Book Chapter

- Shi, J.H. and Wu, F.X. (2010). Assigning probabilities to Mascot peptide identification using logistic regression, Advances in Computational Biology, Edited by Arabnia, Hamid R, Springer, New York, 229-236.

Research Grants

#### 2011-2012

- Principal Investigator, Computational Bioengineering Laboratory, CFI, IOF.
- Principal Investigator, Development of methdologies for modeling and designing biological systems, NSERC, Discovery Grant.

#### 2010-2011

- Principal Investigator, Development of real-time control methodologies for Tandem mass spectrometry, NSERC, Strategic Grant.

#### 2009-2010

- Principal Investigator, Computational Bioengineering Laboratory, CFI, IOF.
- Principal Investigator, Computational Bioengineering Laboratory, Saskatchewan Ministry of Advanced Education, Employment and Labour (AEEL), Provincial ISF Matching Funds.
- Principal Investigator, Development of methdologies for modeling and designing biological systems, NSERC, Discovery Grant.
- Principal Investigator, Development of real-time control methodologies for Tandem mass spectrometry, NSERC, Strategic Grant.
- Principal Investigator, Parameter Estimation of Biological Systems, President NSERC Fund, University of Saskatchewan.

#### 2008-2009

- Principal Investigator, Computational Bioengineering Laboratory, CFI, IOF.
- Principal Investigator, Control engineering and gene regulatory network, NSERC, Discovery Grant.
- Principal Investigator, Development of real-time control methodologies for Tandem mass spectrometry, NSERC, Strategic Grant.

#### 2007-2008

- Principal Investigator, Computational Bioengineering Laboratory, CFI, Leaders Opportunity Funds.
- Principal Investigator, Control engineering and gene regulatory network, NSERC, Discovery Grant.

Teaching

#### 2011-2012

- BIOE898.3 - Introduction to computational systems Biology
- BIOE990.0 - Biomedical Engineering Graduate Seminars
- ME321.3 - Engineering Analysis 2

#### 2010-2011

- BIOE898.3 - Introduction to computational tandem mass spectra
- BIOE990.0 - Biomedical Engineering Graduate Seminars
- ME251.3 - Engineering Analysis 1
- ME321.3 - Engineering Analysis 2
- ME495.6 - Industrial Design Projects
- ME866.3 - System identification and parameter estimation

#### 2009-2010

- BIOE898.3 - Introduction to computational tandem mass spectra
- BIOE990.0 - Biomedical Engineering Graduate Seminars
- ME251.3 - Engineering Analysis 1
- ME321.3 - Engineering Analysis 2
- ME495.6 - Industrial Design Projects
- ME866.3 - System identification and parameter estimation

#### 2008-2009

- ME251.3 - Engineering Analysis 1
- ME321.3 - Engineering Analysis 2
- ME495.6 - Industrial Design Projects
- ME898.3 - Systems identification and Parameter estimation

#### 2007-2008

- ME251.3 - Engineering Analysis 1
- ME321.3 - Engineering Analysis 2
- ME495.6 - Industrial Design Projects

Research Projects

#### 2011-2012

- Computational Bioengineering Laboratory
- Development of methodologies for modeling and designing biological systems
- Development of real-time control methodologies for Tandem mass spectrometry

#### 2010-2011

- Computational Bioengineering Laboratory
- Development of methodologies for modeling and designing biological systems
- Development of real-time control methodologies for Tandem mass spectrometry

#### 2009-2010

- Computational Bioengineering Laboratory
- Control engineering and gene regulatory network
- Development of methodologies for modeling and designing biological systems
- Development of real-time control methodologies for Tandem mass spectrometry

#### 2008-2009

- Computational Bioengineering Laboratory
- Control engineering and gene regulatory network
- Development of real-time control methodologies for Tandem mass spectrometry

#### 2007-2008

- Computational Bioengineering Laboratory
- Control engineering and gene regulatory network
- Development of real-time control methodologies for Tandem mass spectrometry